Inter-individual variation in the adaptive response to heat acclimation

Adaptive divergence in transcriptome response to heat and acclimation in Arabidopsis thaliana plants from contrasting climates

22 Phenotypic variation in stress response has been widely observed within species. This 23 variation is an adaptive response to local climates and is controlled by gene sequence 24 variation and especially by variation in expression at the transcriptome level. Plants 25 from contrasting climates are thus expected to have different patterns in gene 26 expression. Acclimation, a pre-exposure to ...

The human gut virome: inter-individual variation and dynamic response to diet.

Immense populations of viruses are present in the human gut and other body sites. Understanding the role of these populations (the human "virome") in health and disease requires a much deeper understanding of their composition and dynamics in the face of environmental perturbation. Here, we investigate viromes from human subjects on a controlled feeding regimen. Longitudinal fecal samples were ...

Individual variation in response to altitude training.

Moderate-altitude living (2,500 m), combined with low-altitude training (1,250 m) (i.e., live high-train low), results in a significantly greater improvement in maximal O2 uptake (V(02)max) and performance over equivalent sea-level training. Although the mean improvement in group response with this "high-low" training model is clear, the individual response displays a wide variability. To deter...

Variation in the response of barley cultivars to nirrogen fertilizer

Inter-individual variation in midazolam clearance in children

OBJECTIVES To determine the extent of inter-individual variation in clearance of midazolam in children and establish which factors are responsible for this variation. METHODS A systematic literature review was performed to identify papers describing the clearance of midazolam in children. The following databases were searched: Medline, Embase, International Pharmaceutical Abstracts, CINAHL an...